Activated protein C resistance ratio

Description General information Package
insert
Remarks
American Diagnostica APC

Method: Clotting

Activator: Russell’s viper venom factor V dependent prothrombin activator

FV deficient plasma: No

American Diagnostica ACTICLOT APC-R Kit

Method: Clotting

Activator: Russell’s viper venom factor V dependent prothrombin activator

Interferences:  No interference of UFH, LMWH and pentasaccharide

FV deficient plasma: No

American Diagnostica OLIGOBIND APC

Method: EIA

FV deficient plasma: No

Chromogenix Coatest APC Resistance Chromogenix Coatest APC Resistance

Method: Clotting

Activator: activated protein C and calcium

FV deficient plasma: No

Chromogenix Coatest APC Resistance V Chromogenix Coatest APC Resistance V

Method: Clotting

Assay principle: activated protein C and calcium

Interferences: No interference of heparin or oral anticoagulant therapy

FV deficient plasma: Yes

DG APC

Method: Clotting

Activator: Notechis scutatus snake venom factor V dependent prothrombin activator

FV deficient plasma: No

Diagen PCA kit

Method: Clotting

Activator: Snake venom agkistrodon contortrix

FV deficient plasma: Yes and No

Helena Biosciences PCA Ratio Kit

Method: Clotting

Acivator: activated protein C and calcium

FV deficient plasma: Yes

HemosIL FV Leiden (APCR) HemosIL FV Leiden (APCR)

Method: Clotting

Activator: Activated protein C and calcium

Interferences: No interference of heparin (< 1 U/mL) and oral anticoagulant therapy

FV deficient plasma: Yes

Hyphen BioMed Hemoclot Quanti Factor V-L Hyphen BioMed Hemoclot Quanti Factor V-L

Method: Clotting

Activator: Factor Xa in presence of phospholipids and calcium

FV deficient plasma: Yes

Hyphen BioMed Hemoclot V-L Hyphen BioMed Hemoclot V-L

Method: Clotting

Activator: Purified factor IXa with phospholipids and calcium

FV deficient plasma: No

Life Diagnostics GradiLeiden V kit

Method: Clotting

Activator: Snake venom agkistrodon contortrix

Interferences: No interference of heparin and oral anticoagulant therapy

Pentapharm Pefakit APC-R FVL

Method: Clotting

Activator: A snake venom factor Va dependent prothrombin activator

Interferences: No interference of UFH, LMWH and pentasaccharide

FV deficient plasma: No

REA-Clot APC-R (V)

Method: Clotting

Interferences: Interference of UFH and lupus

FV deficient plasma: Yes

Siemens ProC Ac R

Method: Clotting

Interferences: No interference of heparin and high levels of FVII

Siemens ProC Global / FV (with deficient plasma)

Method: Clotting

Interferences: No interference of heparin, (Without factor V deficient plasma Sensitive to deficiencies of factor V Leiden, proteine C and S, certain lupus anticoagulants and high factor VII levels)

FV deficient plasma: Yes

Stago Staclot APC-R

Method: Clotting

Activator: Crotalus viridis helleri venom

Interferences: Interference of low Factor V (<50%) and thrombin inhibitors, No interference of heparin.

FV deficient plasma: Yes

Technoclone APC Resistance kit Technoclone APC Resistance kit

Method: Clotting

Activator: A snake venom factor Va dependent prothrombin activator

FV deficient plasma: No