Antithrombin activity

Company Reagent Link to information Remarks
American Diagnostica ACTICHROME ATIII kit

Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti IIa

BioMedica ACTICHROME ATIII

Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti IIa

Chromogenix Coamatic Antithrombin Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti Xa

Chromogenix Coamatic LR Antithrombin Reagent: Liquid

Method: Chromogenic

Assay principle: Anti Xa

Diagnostic Grifols DG-Chrom AT Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti Xa

Diagnostic Grifols DG-Chrom AT-L Reagent: Liquid

Method: Chromogenic

Assay principle: Anti Xa

Hart Biologicals Ultrasense ATIII-IIa assay kit

Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti IIa

Hart Biologicals Ultrasense ATIII-Xa assay kit Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti Xa

Helena Biosciences Antithrombin Xa Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti Xa

Helena Chromz-AT Method: Chromogenic

Assay principle: Anti Xa

Hyphen BioMed  Biophen Antithrombin Hyphen Biophen Antithrombin Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti Xa

Interferences: No interference of heparin, heparin Cofactor II, alpha-2-macroglobulin or alpha1-Antitrypsin.No significant interference for haemoglobin < 2.5 mg/ml, and bilirubin < 0.1 mg/ml

Hyphen BioMed Biophen AT anti-(h)-Xa LRT Hyphen Biophen AT anti-(h)-Xa LRT Reagent: Liquid

Method: Chromogenic

Assay principle: Anti Xa

Interferences: No interference of heparin, heparin Cofactor II, alpha-2-macroglobulin or alpha1-Antitrypsin.No significant interference for haemoglobin < 2.5 mg/ml, and bilirubin < 0.1 mg/ml

Hyphen BioMed  Biophen AT (anti-lla) Hyphen Biophen AT (anti-lla) Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti IIa

Interferences: No interference of heparin (UFH, LMWH) at usual therapeutic doses

Hyphen BioMed  Biophen AT (LRT) Hyphen Biophen AT (LRT)

Reagent: Liquid

Method: Chromogenic

Assay principle: Anti Xa

Interferences: No interference of heparin, heparin Cofactor II, alpha-2-macroglobulin or alpha1-Antitrypsin.No significant interference for haemoglobin < 2.5 mg/ml, and bilirubin < 0.1 mg/ml

Instrumentation Laboratory, Werfen HemosIL Antithrombin IL HemosIL Antithrombin

Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti Xa

Interferences: No interference of  (UF heparin or LMW
heparin) < 2 U/mL, α1-Antitrypsin < 2 mg/mL, α2-macroglobulin< 7 mg/mL, Heparin
Cofactor II < 3 IU/mL, hemoglobin < 200 mg/dL, bilirubin < 20 mg/dL and triglycerides <
1000 mg/dL.

Instrumentation Laboratory, Werfen HemosIL liquid Antithrombin IL HemosIL liquid Antithrombin

Reagent: Liquid

Method: Chromogenic

Assay principle: Anti Xa

Interferences: No interference of heparin (UF heparin or LMW
heparin) < 4 U/mL, α1-Antitrypsin < 4 mg/mL, α2-macroglobulin < 7 mg/mL, Heparin
Cofactor II < 4 U/mL, hemoglobin < 150 mg/dL, bilirubin < 40 mg/dL and triglycerides <
500 mg/dL.

MediRox AT LR

Reagent: Liquid

Method: Chromogenic

Assay principle: Anti Xa

Nordic Biomarker MRX Antithrombin

Reagent: Liquid

Method: Chromogenic

Assay principle: Anti Xa

Reanal-Ker Spectrolyse Antithrombin III
Roche AT

Reagent: Liquid

Method: Chromogenic

Assay principle: anti IIa

Sekisui Coagpia Antithrombin

Method: Chromogenic

Siemens Healthineers  Berichrom Antithrombin III Siemens Berichrom Anthitrombin III

Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti Xa

Inteferences: Therapeutic doses of hirudin or other direct thrombin inhibitors will cause erroneously
increased antithrombin III activity.

Siemens Healthineers  Innovance Antithrombin Siemens Innovance Antithrombin

Reagent: Liquid

Method: Chromogenic

Assay principle: Anti Xa

Interferences: No interference of heparin < 2 U/ml, heparin cofactor II < 400 mg/L, hirudin < 5 mg/L, therapeutic doses of oral direct factor Xa inhibitors may cause erroneously increased
antithrombin activity.

Stago  STA-Stachrom AT III Stago STA-Stachrom AT III

Reagent: Lyophilized

Method: Chromogenic

Assay principle: Anti IIa

Interferences: No interferences of therapeutic doses of heparin, hemoglobin < 7 g/l, bilirubin < 200 mg/l,
triglycerides < 7.6 g/l, thrombin inhibitors may lead to an over-estimation of the AT level.

Stago, Tcoag TriniCHROM Antithrombin lla Stago TriniCHROM Antitrombin IIa

Method: Chromogenic

Assay principle: Anti IIa

Interferences: Interference of heparin cofactor

Stago, Tcoag TriniCHROM Antithrombin Xa Stago TriniCHROM Antitrombin Xa

Method: Chromogenic

Assay principle: Anti Xa

Interferences: No interference of heparin cofactor II

Technoclone Technochrom ATIII kit Technoclone Technochrom ATIII kit Method: Chromogenic

Assay principle: Anti IIa

Technoclone Technochrom ATIII manual method kit Technoclone Technochrom ATIII manual method kit Method: Chromogenic

Assay principle: Anti IIa

Testzym S ATIII Method: Chromogenic