EQA Programme and prices 2023

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PROGRAMME AND PRICES 2023

#    Prices are excluding VAT and including shipping costs by regular service.

 ANNUAL SUBSCRIPTION
Mandatory for each participant.
 Description                                                                                          
Price
(Euro)
#
Product
code
Annual Subscription Fee  140.50  101

 

MAIN PROGRAMME
Description 
Num-ber of sur-veys 
Survey(s)
2023 
Price
(Euro)#
Product code
M1
M2
M3
M4
Thrombophilia – I:
Antithrombin (activity and antigen), Protein C (activity [chromogenic and clotting] and antigen), Protein S activity, Protein S antigen (total and free)		 4 √ √ √ √   395.00 402
Thrombophilia – II
APC Resistance		 4 √ √ √ √   160.00  417
Coagulation Factor – I
Factor VIII (clot and chromogenic activity), IX (clot and chromogenic activity), XI:C and XII:C		  4 √ √ √ √   199.50 406
Coagulation Factor – II
Factor II:C, V:C, VII:C and X:C		 4 √ √ √ √   199.50 407
Von Willebrand Factor parameters
(antigen, ristocetin cofactor activity,  activity, collagen binding, multimers, Factor VIII)		 4 √ √ √ √ 300.00  408
ADAMTS13 – I (activity and antigen) 4 √ √ √ √   210.00 409
ADAMTS13 – II (antibodies) 2   √   √   137.50  410
ADAMTS13 – III (functional inhibitor) 1   √     100.00 419
Factor XIII (activity and antigen) 4 √ √ √ √   149.50 411
Fibrinolysis – I
Plasminogen, Antiplasmin		 4 √ √ √ √   145.00 412
Fibrinolysis – II
t-PA, PAI-1		 4 √ √ √ √   145.00 413

LUPUS PROGRAMME
Description
Num-ber of sur-veys
Survey(s)
2023
Price
(Euro)#
Product code
L1
L2
L3
L4
Lupus Anticoagulant / Antiphospholipid Antibodies 4 √ √ √ √ 190.00 404

D-DIMER PROGRAMME
Description 
 Num-ber
of sur-veys
Survey(s)
2023
Price
(Euro)
#
Product code
D1
D2
D3
D4
D-Dimer 4 √ √ √ √   145.00 405

SCREEN PROGRAMME
Description
Num-ber
of sur-veys
Survey(s)
2023
Price
(Euro)#
Product code
S1
S2
S3
S4
S5
 S6
 S7
S8
Screen-I: APTT, PT/INR and Fibrinogen 8 √ √ √ √ √ √ √ √ 252.50 501
Screen-II: Thrombin Time, Reptilase Time 8 √ √ √ √ √ √ √ √ 252.50 502

APTT / PT MIXING TEST PROGRAMME
Description 
 Num-ber
of sur-veys 
Survey(s)
2023
Price
(Euro)#
Product code
Mix-1
Mix-2
Mix-3
Mix-4
APTT / PT Mixing Test 4 √ √ √ √  210.00 503

HAEMOPHILIA PROGRAMME
Description
Num-ber of sur-veys
Survey(s)
2023
Price
(Euro)#
Product code
H1
H2
H3
H4
Haemophilia
Factor VIII (clot and chromogenic activity),
Factor IX (clot and chromogenic activity)		 4 √ √ √ √   255.00 418
Factor VIII inhibitor 2   √   √   197.50 202
Factor IX Inhibitor 2 √   √     197.50 201
Emicizumab 2   √   √   197.50 223
Kogenate FS (Bayer) 1     √   100.00 227
Kovaltry (Bayer) 1     √   100.00 228
Jivi (Bayer) 1     √   100.00 229

ANTICOAGULATION PROGRAMME
Description
Num-ber of sur-veys
Survey(s)
2023
Price
(Euro)#
Product code
A1
A2
A3
A4
Unfractionated Heparin Monitoring
(anti-Xa)		 4 √ √ √ √ 130.00 414
Low-Molecular Weight Heparin Monitoring (anti-Xa) 4 √ √ √ √ 130.00 415
Orgaran (anti-Xa) 2   √   √ 66.50 205
Fondaparinux (anti-Xa) 2   √   √ 66.50 206
Rivaroxaban (anti-Xa) 2   √   √ 66.50 207
Apixaban (anti-Xa) 2   √   √ 66.50 208
Edoxaban (anti-Xa) 2   √   √ 66.50 221
Argatroban (anti-IIa, dTT) 2   √   √ 66.50 209
Dabigatran (anti-IIa, dTT) 2   √   √ 66.50 210

THROMBOELASTOGRAPHY PROGRAMME
Description 
 Num-ber
of sur-veys
Survey(s)
2022
Price
(Euro)
#
Product code
T1
T2
T3
 T4
ROTEM delta
∗ 1 instrument / 1 set of samples ROTEM
∗ 2 instruments / 2 sets of samples ROTEM
∗ 3 instruments / 3 sets of samples ROTEM		 4 √ √ √ √

332.50
565.25
798.00

212
213
214
ROTEM sigma
∗ 1 instrument / 1 set of samples ROTEM
∗ 2 instruments / 2 sets of samples ROTEM
∗ 3 instruments / 3 sets of samples ROTEM		 4 √ √ √ √

332.50
565.25
798.00

215
216
217
TEG
∗ 1 instrument / 1 set of samples TEG
∗ 2 instruments / 2 sets of samples TEG
∗ 3 instruments / 3 sets of samples TEG		 4 √ √ √ √

332.50
565.25
798.00

218
219
220
CLOT-PRO
∗ 1 instrument / 1 set of samples CLOT-PRO
∗ 2 instruments / 2 sets of samples CLOT-PRO
∗ 3 instruments / 3 sets of samples CLOT-PRO		 4 √ √ √ √

332.50
565.25
798.00

224
225
226

THROMBIN GENERATION PROGRAMME
Description
Num-ber of sur-veys
Survey(s)
2023
Price
(Euro)#
Product code
TG1
TG2
TG3
TG4
Thrombin Generation Test 2   √   √ 150.00 203

PFA PROGRAMME
Description
Num-ber of sur-veys
Survey(s)
2023
Price
(Euro)#
Product code
P1
P2
P3
P4
PFA-100/200 2   √   √ 472.00 222

HIT PROGRAMME
Description 
 Num-ber
of sur-veys
Survey(s)
2022
Price
(Euro)
#
Product code
HIT1
  
HIT3
  
HIT – I (immunological testing) 2 √   √    225.00 204

ACT PROGRAMME

Note: samples will be distributed separately from other surveys. For details see Survey Schedule 2023
Description  
 Num-ber
of sur-veys 
Survey(s)
2023
Price
(Euro)#
Product code
 
ACT1
 
ACT2
Activated Clotting Time 2   √   √  125.00 504

POCT INR QC PROGRAMME
No annual subscription fee applicable if only participating in the POCT INR QC Programme 
Description  
 Num-ber
of sur-veys 
Survey(s)
2023
Price
(Euro)#
Product code
Q1
Q2
Q3
Q4
POCT INR QC Programme
for CoaguChek INR monitors (any type)		 4 √ √ √ √  452.50 301
  *  Annual shipping costst for countries outside Europe: on request

OTHER SURVEYS
Description
Organised
by
 Num-
ber
of
sur-
veys
Survey
period(s)
2022
Price
(Euro)
#
Product code
Post Analytical Platelet Function EQA (electronic survey) Nascola, USA 2 Spring, Autumn  240.00 701
Platelet Dense Granule exercise (electronic survey) Nascola, USA  2  Spring, Autumn  240.00 704
Case study on bleeding disorders (will be distributed together with survey 2023-3) ECAT  1 2023-3  110.00 703
Case study on anticoagulation bridging (will be distributed together with survey 2023-2) ECAT 1 2023-2 110.00 706
Pre- and post-analytical electronic survey in haemostasis ECAT  1 Autumn   75.00 705

HOMOCYSTEINE PROGRAMME
(in co-operation with the DEKS, Denmark)
Description  
 Num-ber
of sur-veys 
Survey(s)
2023
Price
(Euro)#
Product code
01
02
03
04
Homocysteine 4 √ √ √ √  160.00 1001

MOLECULAR BIOLOGY
(in co-operation with the SPMD, Germany)
 MOLECULAR GENETICS MG1
Survey
name
Description
 Num-
ber
of
sur-
veys
Surveys
2023
Price
(Euro)
#
Product
code
MG1
1/23
MG1
2/23
MG1 Set A For details: see below 2 √ √ ** 601
MG1 Set B For details: see below 2 √ √ **  602
MG1 Set C For details: see below 2 √ √ **  603
MG1 Set D For details: see below 2 √ √ **  604
MG1 Set E For details: see below 2 √ √ **  605
MG1 Set F For details: see below 2 √ √ **  606
MOLECULAR GENETICS MG2 
Survey
name
Description
 Num-
ber
of
sur-
veys
Surveys
2023
Price
(Euro)
#
Product
code
MG2
1/23
MG2
2/3
MG2 Set A For details: see below 2 √ √  **  801
MG2 Set B For details: see below 2 √ √  **  802
MG2 Set C For details: see below 2 √ √  **  803
MG2 Set D For details: see below 2 √ √  **  804
MG2 Set E For details: see below 2 √ √  **  805
MG2 Set F For details: see below 2 √ √  **  806
 PRICES MG1 OR MG2
** MG1 or MG2:
one set:  € 126.00, two sets:  € 202.00, three sets:  € 278.00
four sets:  € 354.00, five sets:  € 403.00, six sets:  € 506.00

 

 DNA SEQUENCING
Survey
name
Description
 Num-
ber
of
sur-
veys
Surveys
2023
Price
(Euro)
#
Product
code
SQ
1/23
SQ
2/23
SQ DNA Sequencing (Sequencing and corresponding diagnostic interpretation) 2 √ √ 264.00 901
DNA ISOLATION
Survey
name
Description
 Num-ber
of
sur-veys
Surveys
2023
Price
(Euro)
#
Product
code
DI
1/23
DI
2/23
 DI DNA Isolation and genotyping For details: see below  2  √ √ 136.00  902
Extra costs for shipment of Molecular Biology surveys Per registration for one or more of the Molecular Biology surveys an annual fee of  € 62.50 will be charged.
Details MG1
Set A:

– FV-Leiden (F5, LRG_553p1:p.Arg534Gln, rs6025)
– FII g20210a, (F2, LRG_551t1:c.*97G>A, rs1799963)
Methylenetetrahydrofolate reductase (MTHFR)
– MTHFR C677T (MTHFR, LRG_726p1:p.Ala222Val, rs1801133)
– MTHFR A1298C (MTHFR, LRG_726p1:p.Glu429Ala, rs1801131)
– PAI-I 4G5G (SERPINE1, LRG_597t1:c.-820_-817G(4_5), rs1799762)
Set B:

– FXIII V34L (F13A1, LRG_549p1:p.Val35Leu, rs5985)
– GPIIIa (ITGB3, LRG_481p1:p.Leu59Pro, rs5918)
– beta-Fibrinogen g-455a (FGB, NM_005141.4:c.-463G>A, rs1800790)
Vitamin K epoxide reductase complex subunit 1 (VKORC1)
– VKORC1 G-1639 (VKORC1, LRG_582:g.3588G>T, rs9923231)
– VKORC1 C1173T (VKORC1, LRG_582t1:c.174-136C>T, rs9934438)
– FXII c46t (F12, LRG_145t1:c.-4T>C, rs1801020)
– FV-H1299R (F5, LRG_553p1:p.His1327Arg, rs1800595)
Set C:

Alpha-1-Antitrypsin, (serpin family A member1)
– AAT-PI*S (SERPINA1, LRG_575p1:p.Glu288Val, rs17580)
– AAT-PI*Z (SERPINA1, LRG_575p1:p.Glu366Lys, rs28929474)
Apolipoprotein E (APOE)
– ApoE2 (APOE, NP_000032.1:p.Arg176Cys, rs7412)
– ApoE4 (APOE, NP_000032.1:p.Cys130Arg, rs429358)
– ApoB100 (APOB, NP_000375.3:p.Arg3527Gln, rs5742904)
– ACE I/D (ACE, NM_000789.3:c.2306-117_2306-116insAF118569.1:g.14094_14382, rs1799752)
– CETP B1/B2 (CETP, NM_000078.3:c.118+279G>A, rs708272)
Set D:

Aldolase, fructose-bisphosphate B (ALDOB )
– AldoB 149 (ALDOB, LRG_1244p1:p.Ala150Pro, rs1800546)
– AldoB 174 (ALDOB, LRG_1244p1:p.Ala175Asp, rs76917243)
– AldoB 334 (ALDOB, LRG_1244p1:p.Asn335Lys, rs78340951)
Hereditäre Hämochromatose (HFE)
– HFE H63D (HFE, LRG_748p1:p.His63Asp, rs1799945)
– HFE C282Y (HFE, LRG_748p1:p.Cys282Tyr, rs1800562)
– HFE S65C (HFE, LRG_748p1:p.Ser65Cys, rs1800730)
– LCT c-13910t (LCT, LRG_338t1:c.-13907C>T, rs4988235)
Nucleotide binding oligomerization domain containing 2 (NOD2)
– NOD R702W (NOD2, LRG_177p1:p.Arg702Trp, rs2066844)
– NOD G908R (NOD2, LRG_177p1:p.Gly908Arg, rs2066845)
– NOD L1007finsC (NOD2, LRG_177p1:p.Leu1007fs, rs2066847)
Set E:

– ATP7B-C3207A (ATP7B, NP_000044.2:p.His1069Gln, rs76151636)
– FSAP Marburg-I (HABP2, NP_004123.1:p.Gly534Glu, rs7080536)
– ITGA2 GpIaIIa C807T (ITGA2, LRG_1001p1:p.Phe253=, rs1126643)
– Col1A1 SP1 (Col1A1, NM_000088.4:c.104-441G>T, rs1800012)
Vitamin D receptor (VDR)
– VDR BsmI (VDR, NM_000376.3:c.1024+283G>A, rs1544410)
– VDR ApaI (VDR, NM_000376.3:c.1025-49G>T, rs7975232)
– VDR TaqI (VDR, NP_000367.1:p.Ile352=, rs731236)
Set F:

– Factor VII (R353Q) (F7, LRG_554p1:p.Arg413Gln, rs6046)
– AT3 Cambridge Typ I/II (SERPINC1, LRG_577p1:p.Ala416Pro/Ser, rs121909548)
– CYP3A5*3 (CYP3A5, NM_000777.5:c.219-237A>G, rs776746)
Details MG2
Set A:

Thiopurine S-methyltransferase (TPMT)
– TPMT*2 (TPMT, LRG_874p1:p.Ala80Pro, rs1800462)
– TPMT*3B (TPMT, LRG_874p1:p.Ala154Thr, rs1800460)
– TPMT*3C (TPMT, LRG_874p1:p.Tyr240Cys, rs1142345)
– CYP2C8*3 (CYP2C8, NP_000761.3:p.Lys399Arg, rs10509681)
Cytochrom P450 2C9 (CYP2C9)
– CYP2C9*2 (CYP2C9, LRG_1195p1:p.Arg144Cys, rs1799853)
– CYP2C9*3 (CYP2C9, LRG_1195p1:p.Ile359Leu, rs1057910)
– UGT1A1*28 (UGT1A1, LRG_733t1:c.-41_-40dup, rs3064744)
Dihydropyrimidine dehydrogenase (DPYD)
– DPYD*2A (DPYD, LRG_722t1:c.1905+1G>A, rs3918290)
– DPYD*13 (DPYD, LRG_722p1:p.Ile560Ser, rs55886062)
– DPYD p.D949V (DPYD, LRG_722p1:p.Asp949Val, rs67376798)
– DPYD c.1129-5923C>G (DPYD, LRG_722:g.346167C>G, rs75017182)
– DPYD c.1236G>A (DPYD, LRG_722p1:p.Glu412=, rs56038477)
– DPYD HapB3 (DPYD, LRG_722:g.346167C>G, rs75017182 or DPYD, LRG_722p1:p.Glu412=, rs56038477)
– DPD activity score acc. to CPIC
– BCHE A (D70G) (BCHE, NP_000046.1:p.Asp98Gly, rs1799807)
– BCHE K (A567T) (BCHE, NP_000046.1:p.Ala567Thr, rs1803274)
Set B:

KRAS proto-oncogene, GTPase (KRAS)
– KRAS p.G12 (KRAS, LRG_344p1:p.Gly12Cys/Arg/Ser, rs121913530)
– KRAS p.G12 (KRAS, LRG_344p1:p.Gly12Val/Ala/Asp, rs121913529)
– KRAS p.G13 (KRAS, LRG_344p1:p.Gly13Cys/Arg/Ser, rs121913535)
– KRAS p.G13 (KRAS, LRG_344p1:p.Gly13Val/Ala/Asp, rs112445441)
– KRAS p.Q61 (KRAS, LRG_344p1:p.GLn61Glu/Lys, rs121913238)
– KRAS p.Q61 (KRAS, LRG_344p1:p.GLn61Leu/Arg/Pro, rs121913240)
– KRAS p.Q61 (KRAS, LRG_344p1:p.GLn61His, rs17851045)
BRAF proto-oncogene, serine/threonine kinase (BRA)
– BRAF p.V600E (BRAF, LRG_299p1:p.Val600Glu, rs113488022)
– BRAF p.V600K (BRAF, LRG_299p1:p.Val600Lys, rs121913227)
– cKIT p.D816V (KIT, LRG_307p1:p.Asp816Val, rs121913507)
NRAS proto-oncogene, GTPase (NRAS)
– NRAS p.Q61 (NRAS, LRG_92p1:p.Gln61Ter/Glu/Lys, rs121913254)
– NRAS p.Q61 (NRAS, LRG_92p1:p.Gln61Leu/Arg/Pro, rs11554290)
– NRAS p.Q61 (NRAS, LRG_92p1:p.Gln61His, rs121913255)

Set C:

– HLA-B*27 (HLA-B, NM_005514.8)
– TNF alpha 238 (TNF, NM_000594.3:c.-418G>A, rs361525)
– TNF alpha 308 (TNF, NM_000594.3:c.-488G>A, rs1800629)
Set D:

Cytochrom P450 2D6 (CYP2D6)
– CYP2D6*2-296 (CYP2D6, LRG_303p1:p.Arg296Cys, rs16947)
– CYP2D6*2-486 (CYP2D6, LRG_303p1:p.Ser486Thr, rs1135840)
– CYP2D6*3 (CYP2D6, LRG_303p1:p.Arg259fs, rs35742686)
– CYP2D6*4 (CYP2D6, LRG_303t1:c.506-1G>A, rs3892097)
– CYP2D6*6 (CYP2D6, LRG_303p1:p.Trp152fs, rs5030655)
– CYP2D6*7 (CYP2D6, LRG_303p1:p.His324Pro, rs5030867)
– CYP2D6*8 (CYP2D6, LRG_303p1:p.Gly169Ter, rs5030865)
– CYP2D6*9 (CYP2D6, LRG_303p1:p.Lys281del, rs5030656)
– CYP2D6*10 (CYP2D6, LRG_303p1:p.Pro34Ser, rs1065852)
– CYP2D6*17 (CYP2D6, LRG_303p1:p.Thr107Ile, rs28371706)
– CYP2D6*35 (CYP2D6, LRG_303p1:p.Val11Met, rs769258)
– CYP2D6*41 (CYP2D6, LRG_303t1:c.985+39G>A, rs28371725)
– CYP2D6*5 (CYP2D6, Deletion)
– CYP2D6*xN (CYP2D6, Duplikation/Amplifikation)
– Cytochrom P450 2C19 (CYP2C19)
– CYP2C19*2 (CYP2C19, NP_000760.1:p.Pro227=, rs4244285)
– CYP2C19*3 (CYP2C19, NP_000760.1:p.Trp212Ter, rs4986893)
– CYP2C19*17 (CYP2C19, NG_008384.3:g.4220C>T, rs12248560)
Set E:

– HLA B*57:01 (HLA-B, NM_005514.8)
– Cytochrom P450 2B6 (CYP2B6)
CYP2B6*4 (CYP2B6, LRG_1267p1:p.Lys262Arg, rs2279343)
CYP2B6*9 (CYP2B6, LRG_1267p1:p.Gln172His, rs3745274)
CYP2B6*6 (CYP2B6, LRG_1267p1:p.[Lys262Arg, Gln172His], rs2279343 und rs3745274)
– ABCB1 c.3435C>T (ABCB1, NP_001335875.1:p.Ile1145=, rs1045642)
– CCR5-del32bp (CCR5, NP_001381712.1:p.Ser185fs, rs333)
Set F:

– IL28B (C/T Polymorphismus) (IFNL4, NM_001276254.2:c.151-152G>A, rs12979860)
– IL6 G(-174)C (IL6, NG_011640.1:g.4880C>G, rs1800795)
– CYP3A4*22 (CYP3A4, NM_017460.6:c.522-191C>T, rs35599367)
Details DNAIsolation and genotyping
Set:

– FV-Leiden (F5, LRG_553p1:p.Arg534Gln, rs6025)
– FV-H1299R (F5, LRG_553p1:p.His1327Arg, rs1800595)
– FV-Cambridge (F5, LRG_553p1:p.Arg334Thr, rs118203906)
– FV-Hong-Kong (F5, LRG_553p1:p.Arg334Gly, rs118203905)
– FII g20210a (F2, LRG_551t1:c.*97G>A, rs1799963)
Methylenetetrahydrofolate reductase (MTHFR)
– MTHFR C677T (MTHFR, LRG_726p1:p.Ala222Val, rs1801133)
– MTHFR A1298C (MTHFR, LRG_726p1:p.Glu429Ala, rs1801131)
Hereditäre Hämochromatose (HFE)
– HFE H63D (HFE, LRG_748p1:p.His63Asp, rs1799945)
– HFE C282Y (HFE, LRG_748p1:p.Cys282Tyr, rs1800562)
– HFE S65C (HFE, LRG_748p1:p.Ser65Cys, rs1800730)