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Today we are pleased to send you our digital Newsletter. With this Newsletter we aim to provide you with some important ECAT information, relevant articles and reviews on publications in the fields of quality control and/ or laboratory diagnosis in thrombosis & haemostasis.
Enjoy reading them, Petra ter Hark

Recently we were informed by the Dutch Council for Accreditation that the ECAT Foundation had successfully passed the most recent accreditation audit according to the ISO/IEC standard 17043:2010. On the ECAT website ( you can find our accreditation certificate as well as the scope of our accreditation.

ECAT Information:
ECAT Symposium 

On Thursday 8 and Friday 9 November 2018 the 11th ECAT symposium will be held in the Holiday Inn Hotel in Leiden, The Netherlands. An attractive programme for this symposium has been arranged. Here you can find the details of the programme. Soon more information will be available on the ECAT website ( Select the option Meeting.
Please reserve these dates.

ECAT Course

In conjunction with the ECAT symposium a course, entitled “Quality assurance of the total testing process” will be organised on Wednesday 7 November 2018. The course focuses on “Quality Assurance requirements from ISO 15189”, “Method and equipment validation” and “Error detection by internal and external quality control”. More details can be found Here.

Satellite Symposium

In conjunction the ECAT symposium a satellite symposium, entitled “Laboratory measurement of extended half-life FVIII and FIX products” will be organised on Wednesday 7 November 2018. With the appearance of extended half-life FVIII and FIX products for the treatment of haemophilia patients laboratories are faced with new challenges. During this satellite symposium various aspects with respect to the laboratory measurement of these products will be discussed by a panel of internationally well-recognised speakers. More details can be found Here.

ECAT Information: Special survey on Extended Half-Life FIX products 

In co-operation with UKNEQAS (United Kingdom) and RCPA (Australia) the ECAT Foundation will organise a special survey for the measurement of extended half-life FIX products in plasma. The following products are included: Idelvion (CSL Behring), Alprolix (Sobi), Refixia/Rebinyn (Novo Nordisk) and BeneFIX (Pfizer). Laboratories are asked to measure these samples by their regular method (one-stage clotting assay and/or chromogenic assay) used in the laboratory. For each product two different samples are supplied. Each participant will receive the complete set of samples. If you would like to particiapte in the special survey, please register via the following link:
Participation is free of charge.

Case Report: A patient with acquired factor X deficiency and metastatic carcinoma of the bladder: is there a link between metastasis and factor deficiency in solid tumours? 

Acquired deficiency of factor X is commonly found during antivtamin K therapy for the prevention of thrombosis or as a consequence of liver disease. Less frequently, it has been observed as an isolated deficiency in a number of disease states. It has been associated with the amyloidosis and haematological malignancies, and a few non-amyloid-related cases have been reported. Association with solid tumours is rare. We would like to present a patient with a transitional cell carcinoma who developed a factor X deficiency.
Read more

Literature Review: International normalised ration (INR) testing in Europe: between-laboratory comparability of test results by Quick and Owren reagents

(P. Meijer et al. Clin Chem Lab Med 2018; ahead of print)
Within the framework of the EQALM a study was designed to obtain an overview of the analytical quality of the prothrombin time, reported as INR and to asses the variation of INR results between European laboratories, the difference between Quick-type and Owren-type methods and the effect of using local INR calibration or not. In addition, the variation in INR results obtained for a single donation in comparison with a pool of several plasmas was assessed.
Read more
Upcoming Events
23rd Congres of EHA
14-17 June, Stockholm, Sweden

10th Congress of the APSTH 
28-30 June 2018, Sapporo, Japan
64th Annual SSC Meeting 
17-21 July 2018, Dublin, Ireland
2nd Joint Meeting of the ISFP and the PA Workshop 

3-7 September 2018, Edinburgh, UK

ECTH 2018 
24-28 October 2018, Marseille, France

For more events, please have a look into our Calendar.

June 2018, Issue 13
ECAT Foundation
ECAT Information
Case report
Literature Review
Upcoming Events
Diagnostic Corner
Pharma Corner
Editor in Chief:
P. ter Hark

Editorial Board:
P. ter Hark
P. Meijer

Advisory Committee:
E. van Cott
K. Devreese
D. Peetz
A. Stroobants

+31.(0)71.3030910 9
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